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Results for "

Methionine Aminopeptidase

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Peptides

4

Recombinant Proteins

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120868
    TP-004

    		MetAP Metabolic Disease
    TP-004 is a potent and reversible inhibitor of methionine aminopeptidase 2 (MetAP2), with an IC50 of 6 nM .
    TP-004
  • HY-101932
    TNP-470

    AGM-1470

    		 Aminopeptidase Cardiovascular Disease Cancer
    TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor.
    TNP-470
  • HY-133016A
    (R)-M8891

    		MetAP Others
    (R)-M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor .
    (R)-M8891
  • HY-13731
    PPI-2458

    		MetAP Inflammation/Immunology Cancer
    PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 (MetAP-2). PPI-2458 can be used for arthritis and lymphoma research .
    PPI-2458
  • HY-109188
    Relzomostat

    		MetAP Metabolic Disease
    Relzomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor.Relzomostat may be useful for the research of obesity, type 2 diabetes, and other obesity-associated conditions .
    Relzomostat
  • HY-P4553
    H-Met-Pro-OH

    		Amino Acid Derivatives Others
    H-Met-Pro-OH is a dipeptide containing methionine and proline. H-Met-Pro-OH is a substrate for aminopeptidase P (APP) and skin fibroblast prolidase .
    H-Met-Pro-OH
  • HY-143249
    MtMetAP1-IN-1

    		Bacterial Infection
    MtMetAP1-IN-1 is an inhibitor of Mycobacterium tuberculosis (Mtb), targeting methionine aminopeptidase 1 (MetAP1). MtMetAP1-IN-1 exerts antimycobacterial activity .
    MtMetAP1-IN-1
  • HY-157518
    OJT008

    		Bacterial Infection
    OJT008 is an inhibitor of MtMetAP1c. OJT008 inhibits NiCl2- and CoCl2 activated MtMetAP1c with IC50s of 11 and 40 μM, respectively. OJT008 can used to study tuberculosis .
    OJT008
  • HY-133016
    M8891

    		MetAP Cardiovascular Disease Cancer
    M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 54 nM and a Ki of 4.33 nM. M8891 does not inhibit MetAP-1 (IC50>10 µM) . M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral activity .
    M8891
  • HY-158006
    SDX-7539

    		MetAP Cancer
    SDX-7539 is a selective inhibitor for Methionine aminopeptidase type 2 (MetAP2). SDX-7539 inhibits proliferarion of HUVECs with an IC50 of 120 μM. SDX-7539 exhibits antitumor activity in NSCLC xenograft athymic nude mice .
    SDX-7539
  • HY-121123
    Adamantanine

    2-Aminoadamantane-2-carboxylic acid

    		 Aminopeptidase Cancer
    Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
    Adamantanine

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